Curriculums and credits
1. Introduction to Integrative Bioscience
【fiscal year 2013】
● Course title
● Course title
Introduction to Integrative Bioscience
● Credit
1
● Lecturer
Toshitaka Fujisawa (CPIS, SOKENDAI)
● Place
Yamate campus, building 3, 9F Seminar room B
The lectures are delivered to remote campuses by remote lecture delivering systems.
●Contents of subject
The educational program for Integrative bioscience will be introduced, overviewing contemporary bioscience and discussing the features and necessity of the Integrative bioscience.
●Course objectives
First, the educational program for Integrative bioscience will be introduced. Then, driving forces for rapid development of biology are reviewed from a historical point of view, and the features of contemporary life science are overviewed. Based on these reviews what the Integrative bioscience is and why it is necessary are discussed5/1, 8, 1. Particularly, it is emphasized that a large volume of information on sequences and structures of genome, RNA, proteins, sugars, metabolites etc. and that of spacio-temporal expression of these molecules are integrated to understand their meaning at a cell, tissue, organ or organism level and to unravel the mechanisms of high order biological functions, diseases, environmental responses etc.
●Schedule
For the fiscal year 2013
4/25,5/9,16,23,6/6,13,20,27 Thursday 10:00 -12:00
●Contents
(1) Introduction of the educational program for Integrative bioscience
(2) Driving forces for biology
(3) Characteristics of contemporary bioscience 1
(4) Characteristics of contemporary bioscience 2
(5) Characteristics of contemporary bioscience 3
(6) Characteristics of contemporary bioscience 4
(7) What is Integrative bioscience ?
(8) Significance of Integrative bioscience
●Lecture materials and readings:
No specific textbook is used. References will be introduced in the lecture when necessary.
● Grades
The grade is determined by reports/homeworks and attendance at the lectures. 60 points are necessary to get the credit.
☆For the details of schedule, please refer "Schedule of the classes".

☆For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
2. Structual Biomolecular Science
【fiscal year 2013】
●Course title
★Structual Biomolecular Science (Dept. Struct. Mol. Sci.) fiscal year 2013
Functional Biomolecular Science (Dept. Funct. Mol. Sci.) fiscal year 2014
●Credit
2
●Appropriate grade level and Eligible Departments 1st-5th grades
●Lecturer(s)
Prof. Shigetoshi Aono (IMS Dept. of Life and Coordination-Complex Molecular Science)
Assoc. Prof. Yuji Furutani (IMS Dept. of Life and Coordination-Complex Molecular Science)
●Schedule
the fiscal year 2013 12/17,18,19,20 (10:30-12:30,13:30-15:30)
1.Metals in biology
2.Transcriptional regulation in response to environmental conditions
3.Biogenesis of metalloproteins and translational regulation
4.Homeostasis of transition metal ions in cells
5.Biological signal transduction involving metalloproteins
6.Biological energy metabolism
7.Biological and artificial membranes
8.Structure and function of membrane proteins
9.Signal perception: Bioelectrical signal, Molecular mechanisms of ion channel, transporter, and light receptors
10.Motion of proteins: Molecular motor, ATP synthase
11.Recent topics
●Place
Myodaiji Research Office 301,IMS
The lectures are delivered to remote campuses by remote lecture delivering systems.
●Prerequisites and Styles:
●Course objectives:
To get basic knowledge about life sciences and to understand the molecular mechanisms of biological processes.
●Contents:
The molecular mechanisms of various biological processes will be lectured in this course. Especially, the molecular mechanisms of the following topics will be provided: DNA replication, transcription and translation of DNA, cellular homeostasis, biological energy conversion such as respiration and photosynthesis, sensory receptors, bioelectronics in a neuron, and some recent research topics.
●Lecture materials and readings:
1.Principles of Bioinorganic Chemistry, Stephen J. Lippard, Jeremy M. Berg, University Science Book
2.Membrane Structural Biology With Biochemical and Biophyscial Foundations, Mary Luckey, Cambridge University Press
●Grades:
To earn the credit, attendance of more than 60% of all the lectures and submission of a report on the subject given in the lecture are required. The grade will be estimated based upon the attendance and the report. The credit will be awarded if the grade is 60/100 or higher.
☆For the details of schedule, please refer "Schedule of the classes".
●Course title
★Structual Biomolecular Science (Dept. Struct. Mol. Sci.) fiscal year 2013
Functional Biomolecular Science (Dept. Funct. Mol. Sci.) fiscal year 2014
●Credit
2
●Appropriate grade level and Eligible Departments 1st-5th grades
●Lecturer(s)
Prof. Shigetoshi Aono (IMS Dept. of Life and Coordination-Complex Molecular Science)
Assoc. Prof. Yuji Furutani (IMS Dept. of Life and Coordination-Complex Molecular Science)
●Schedule
the fiscal year 2013 12/17,18,19,20 (10:30-12:30,13:30-15:30)
1.Metals in biology
2.Transcriptional regulation in response to environmental conditions
3.Biogenesis of metalloproteins and translational regulation
4.Homeostasis of transition metal ions in cells
5.Biological signal transduction involving metalloproteins
6.Biological energy metabolism
7.Biological and artificial membranes
8.Structure and function of membrane proteins
9.Signal perception: Bioelectrical signal, Molecular mechanisms of ion channel, transporter, and light receptors
10.Motion of proteins: Molecular motor, ATP synthase
11.Recent topics
●Place
Myodaiji Research Office 301,IMS
The lectures are delivered to remote campuses by remote lecture delivering systems.
●Prerequisites and Styles:
●Course objectives:
To get basic knowledge about life sciences and to understand the molecular mechanisms of biological processes.
●Contents:
The molecular mechanisms of various biological processes will be lectured in this course. Especially, the molecular mechanisms of the following topics will be provided: DNA replication, transcription and translation of DNA, cellular homeostasis, biological energy conversion such as respiration and photosynthesis, sensory receptors, bioelectronics in a neuron, and some recent research topics.
●Lecture materials and readings:
1.Principles of Bioinorganic Chemistry, Stephen J. Lippard, Jeremy M. Berg, University Science Book
2.Membrane Structural Biology With Biochemical and Biophyscial Foundations, Mary Luckey, Cambridge University Press
●Grades:
To earn the credit, attendance of more than 60% of all the lectures and submission of a report on the subject given in the lecture are required. The grade will be estimated based upon the attendance and the report. The credit will be awarded if the grade is 60/100 or higher.
☆For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
3. Bioinformatics Practical Course
【Fiscal year 2013】
●Course title
Bioinformatics Practical Course Lecture and tutorial
*This subject is the same as "Bioinformatics Practical Course" in The Sokendai Brain Science Joint Program.
●Credit
One credit
●Appropriate grade level and Eligible Departments
All Departments
●Lecturer(s)
Satoru Kobayashi (NIBB)
Shuji Shigenobu (NIBB)
●Schedule
schedule for the second semester in 2013
9:00-10:30 and 11:00-12:30 on Thursday (10/24,11/7,11/14,11/21)
(1) Introduction to Genomics Shuji Shigenobu (NIBB)
(2) Biological sequence analysis 1 Shuji Shigenobu (NIBB)
(3) Biological sequence analysis 2 Shuji Shigenobu (NIBB)
(4) Lab tutorial 1(This is NOT delivered by the remote lecture system) Shuji Shigenobu (NIBB)
(5) Gene expression and transcriptome Shuji Shigenobu (NIBB)
(6) Proteomics and functional genomics Shuji Shigenobu (NIBB)
(7) Lab tutorial 2 (Biological database) Shuji Shigenobu (NIBB)
(8) Current topics on genome Shuji Shigenobu (NIBB)
●Place
Yamate campus, building 3, 9F Seminar room B [Oct 24, Nov 14]
1F seminar room 1 in National Institute of Basic Biology [Nov 7, Nov 21]
●Course objectives
To understand basic principles in biological sequence analyses.
To obtain basic skills in genomic and proteomic analyses.
To understand current topics and future directions in bioinformatics.
●Contents
Basic knowledge and skills in analyses of genome, proteome, and transcriptome will be introduced in lectures and tutorials.
●Grades
Synthetically judged by sufficient attendance to the lectures and a reporting assignment.
●Prerequisites and Styles
No particular background knowledge is required.
●Lecture materials and readings
Laptop computers will be ready and useful database will be introduced on site for the tutorial.
☆For the details of schedule, please refer "Schedule of the classes".

●Course title
Bioinformatics Practical Course Lecture and tutorial
*This subject is the same as "Bioinformatics Practical Course" in The Sokendai Brain Science Joint Program.
●Credit
One credit
●Appropriate grade level and Eligible Departments
All Departments
●Lecturer(s)
Satoru Kobayashi (NIBB)
Shuji Shigenobu (NIBB)
●Schedule
schedule for the second semester in 2013
9:00-10:30 and 11:00-12:30 on Thursday (10/24,11/7,11/14,11/21)
(1) Introduction to Genomics Shuji Shigenobu (NIBB)
(2) Biological sequence analysis 1 Shuji Shigenobu (NIBB)
(3) Biological sequence analysis 2 Shuji Shigenobu (NIBB)
(4) Lab tutorial 1(This is NOT delivered by the remote lecture system) Shuji Shigenobu (NIBB)
(5) Gene expression and transcriptome Shuji Shigenobu (NIBB)
(6) Proteomics and functional genomics Shuji Shigenobu (NIBB)
(7) Lab tutorial 2 (Biological database) Shuji Shigenobu (NIBB)
(8) Current topics on genome Shuji Shigenobu (NIBB)
●Place
Yamate campus, building 3, 9F Seminar room B [Oct 24, Nov 14]
1F seminar room 1 in National Institute of Basic Biology [Nov 7, Nov 21]
●Course objectives
To understand basic principles in biological sequence analyses.
To obtain basic skills in genomic and proteomic analyses.
To understand current topics and future directions in bioinformatics.
●Contents
Basic knowledge and skills in analyses of genome, proteome, and transcriptome will be introduced in lectures and tutorials.
●Grades
Synthetically judged by sufficient attendance to the lectures and a reporting assignment.
●Prerequisites and Styles
No particular background knowledge is required.
●Lecture materials and readings
Laptop computers will be ready and useful database will be introduced on site for the tutorial.
☆For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
4. Imaging Science
【Fiscal year 2013】
● Course title
● Course title
Imaging Science
● Course objectives
We are now enjoying various imaging techniques in the cutting edge of biological and medical sciences. The well known from old is microscopic techniques and nowadays MRI, PET and MEG are popular imaging tools. Imaging science is a novel discipline trying to integrate the old and the new. It consists of three categories, hardware tools to generate primary data, software tools to digitally process the primary data and imaging analysis to quantitatively analyze imaging digital data. In this lecture, 3D imaging and quantitative image analysis are in a particular focus. The former includes the theoretical background of 3D imaging and its practical applications with electron and light microscopy. The latter includes a novel quantitative image analysis based on various numerical algorithms.
This lecture series welcome students who are eager to learn a basic theory to practical applications in a field of imaging science.
This lecture series welcome students who are eager to learn a basic theory to practical applications in a field of imaging science.
● Credit
1
● Appropriate grade level and Eligible Departments:
1st-5th grades
●Lecturers
Kuniaki Nagayama (NIPS)
Naofumi Iwama (NINS)
Kazuyoshi Murata (Dept. Physiol. Sci. )
Shigenori Nonaka (Dept. Basic Biol. )
Hideji Murakoshi (Dept. Physiol. Sci.)
Yoshitaka Kimori (Centr. Novel Sci. Initiatives)
Kuniaki Nagayama (NIPS)
Naofumi Iwama (NINS)
Kazuyoshi Murata (Dept. Physiol. Sci. )
Shigenori Nonaka (Dept. Basic Biol. )
Hideji Murakoshi (Dept. Physiol. Sci.)
Yoshitaka Kimori (Centr. Novel Sci. Initiatives)
●Schedule
Feburaru 18 (Tue), 19 (Wed), 2014
● Place
Yamate campus, building 3, 9F Seminar room B
(19 am : Yamate campus, building 3, 9F Seminar room A)
(19 am : Yamate campus, building 3, 9F Seminar room A)
●Contents:
TBD
TBD
● Grades
⇒ Syllabus
PDF
5. Integrative Bioscience Series
【fiscal year 2013】
●Course title
●Course title
Integrative Bioscience Series
●Credit
1
●Appropriate grade level and Eligible Departments
1st-5th grades
●Lecturers
Toshitaka Fujisawa (CPIS, SOKENDAI)
Tatsuya Ohota(Dept. Evolutional Studies Biosystems)
Masaki Sasai (Nagoya University )
Kazuhiro Ikenaka (Dept. Physiol. Sci. )
Masanao Sato (Dept. Basic. Sci.)
Yuji Furutani (Dept. Funct. Sci.)
Daiki Kitagawa (Dept. Genetics)
Syuhei Mano (Dept. Statistical Sci.)
Tatsuya Ohota(Dept. Evolutional Studies Biosystems)
Masaki Sasai (Nagoya University )
Kazuhiro Ikenaka (Dept. Physiol. Sci. )
Masanao Sato (Dept. Basic. Sci.)
Yuji Furutani (Dept. Funct. Sci.)
Daiki Kitagawa (Dept. Genetics)
Syuhei Mano (Dept. Statistical Sci.)
●Schedule
2013:July 1 and 8
July 1 (Mon)
9:00-10:30 "Molecular evolution of biosystems - immune system as an example - " Tatsuya Ohota
(Hayama Campus ,TV Conference Room, Library Building 3F)
10:30-12:00 "Landscape theories in bioscience" Masaki Sasai
(Yamate campus, building 3, 9F Seminar room B)
13:00-14:30 “Function and diseases of glial cells” Kazuhiro Ikenaka
(Yamate campus, building 3, 9F Seminar room B)
14:30-16:00 "Network Biology: a new perspective towards understanding complex biological
systems" Masanao Sato(Yamate campus, building 3, 9F Seminar room B)
July 8 (Mon)
9:00-10:30 Yuji Furutani (Yamate campus, building 3, 9F Seminar room B)
10:30-12:00 "Cell biology using a combination of multi-disciplinary approaches" Daiki Kitagawa
(3F seminar room of the library in National Institute of Genetics)
13:00-14:00 “Inference about genome diversity by stochastic modeling” Syuhei Mano
(The Institute of Statistical Mathematics ,2F Seminar room1 D222)
14:00-15:00 "Summary of Integrative Bioscience Series" Toshitaka Fujisawa (CPIS, SOKENDAI)
The lectures are delivered to remote campuses by remote lecture delivering systems.
July 1 (Mon)
9:00-10:30 "Molecular evolution of biosystems - immune system as an example - " Tatsuya Ohota
(Hayama Campus ,TV Conference Room, Library Building 3F)
10:30-12:00 "Landscape theories in bioscience" Masaki Sasai
(Yamate campus, building 3, 9F Seminar room B)
13:00-14:30 “Function and diseases of glial cells” Kazuhiro Ikenaka
(Yamate campus, building 3, 9F Seminar room B)
14:30-16:00 "Network Biology: a new perspective towards understanding complex biological
systems" Masanao Sato(Yamate campus, building 3, 9F Seminar room B)
July 8 (Mon)
9:00-10:30 Yuji Furutani (Yamate campus, building 3, 9F Seminar room B)
10:30-12:00 "Cell biology using a combination of multi-disciplinary approaches" Daiki Kitagawa
(3F seminar room of the library in National Institute of Genetics)
13:00-14:00 “Inference about genome diversity by stochastic modeling” Syuhei Mano
(The Institute of Statistical Mathematics ,2F Seminar room1 D222)
14:00-15:00 "Summary of Integrative Bioscience Series" Toshitaka Fujisawa (CPIS, SOKENDAI)
The lectures are delivered to remote campuses by remote lecture delivering systems.
●Place
Yamate campus, building 3, 9F Seminar room B
3F seminar room of the library in National Institute of Genetics
3F seminar room of the library in National Institute of Genetics
Hayama Campus ,TV Conference Room, Library Building 3F
The Institute of Statistical Mathematics ,2F Seminar room1 (D222)
The Institute of Statistical Mathematics ,2F Seminar room1 (D222)
●Course objectives
To learn biological processes at various levels, covering molecular, cellular and individual processes, with broader perspective in an integrative manner, seven departments (Departments of Structural Molecular Science, Functional Molecular Science, Basic Biology, Physiological Sciences, Genetics, Evolutional Studies of Biosystems, and Statistical Science), which participate in the Integrative Bioscience Education Program, offer a series of the following lectures in an understandable manner for students in the first and second years.
●Contents:
TBD
●Grades
Sufficient attendance to the lecture and a score of some reports
☆For the details of schedule , please refer "Schedule of the classes".

☆For the details of schedule , please refer "Schedule of the classes".
⇒ Syllabus
PDF
6. Introduction to Biomolecular Simulation
【fiscal year 2013】
● Course title
● Credit
1 credit
● Appropriate grade level and Eligible Departments
1st-5th grades
● Lecturers
● Place
● Course title
Introduction to Biomolecular Simulation
● Course objectives
Basic theories and computational methods for molecular simulations for biomoleculs will be introduced. For example, basic and various advanced methodologies for molecular simulations as well as fundamentals of analytical mechanics and statistical mechanics will be lectured.● Course objectives
● Credit
1 credit
● Appropriate grade level and Eligible Departments
1st-5th grades
● Lecturers
Prof Shinji Saito (IMS )
Assoc. Prof. Hisashi Okumura(IMS)
Assoc. Prof. Hisashi Okumura(IMS)
● Place
Myodaiji Research Office 301,IMS
The lectures are delivered to remote campuses by remote lecture delivering systems.
● Schedule
schedule for the second semester in 2013:December 10 and 12
The lectures are delivered to remote campuses by remote lecture delivering systems.
●Grades
Sufficient attendance to the lecture and a score of some reports
☆For the details of schedule, please refer "Schedule of the classes".

● Schedule
schedule for the second semester in 2013:December 10 and 12
The lectures are delivered to remote campuses by remote lecture delivering systems.
●Grades
Sufficient attendance to the lecture and a score of some reports
☆For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
7. Integrative Evolutionary Studies
【fiscal year 2013】
●Course title
●Course title
Integrative Evolutionary Studies
●Credit
2 credits
●Appropriate grade level and Eligible Departments
1st-5th grades
●Lecturer:
Yoko Satta (Dept. Evolutionary Studies of Biosystems)
●Schedule:
2014/1/8 (10:30-12:00)・1/9 (15:00-18:00, )・
2014/1/29・30・2/5・6(10:30-12:00, 13:00-14:30,14:30-16:00)
●Place: Hayama campus, Library (3F) TV conference room
●Contents of subject:
Biosystems on the earth can be classified into systems with different levels of complexity, from a cell to society. This course is to discuss evolution of such systems from viewpoints of "elements (members) in each system", " interaction between elements" and "theory to describe this interaction".
●Course objectives:
General view of “Evolution of life” will be introduced. Then the mechanism of molecular evolution, especially at genomic and DNA level will be described. Human evolution will be reviewed from viewpoints of genetics, adaptation and environmental changes. Mathematical and theoretical biology and animal behavior will also be reviewed with a special reference to the contribution to development of evolutionary understanding of “life”.
●Contents:
1. Tree of life (1/8・9: Mariko Hasegawa)
2. Basis of molecular evolution (1/29: Yoko Satta)
3. Human evolution – genetics, adaptation, and environment - (1/30: Jun Gojobori)
4. Prediction for future - mathematical and theoretical biology - (2/5: Hisashi Ohtsuki)
5. Animal Behaviour – mechanism and evolution - (2/6: Nobuyuki Kutsukake)
●Lecture materials and readings:
No specific textbook is used. References will be introduced in the lecture when necessary.
●Grades:
The grade is determined by reports/homeworks and attendance at the lectures. 60 points are necessary to get the credit.
☆For the details of schedule, please refer "Schedule of the classes".

2 credits
●Appropriate grade level and Eligible Departments
1st-5th grades
●Lecturer:
Yoko Satta (Dept. Evolutionary Studies of Biosystems)
●Schedule:
2014/1/8 (10:30-12:00)・1/9 (15:00-18:00, )・
2014/1/29・30・2/5・6(10:30-12:00, 13:00-14:30,14:30-16:00)
●Place: Hayama campus, Library (3F) TV conference room
●Contents of subject:
Biosystems on the earth can be classified into systems with different levels of complexity, from a cell to society. This course is to discuss evolution of such systems from viewpoints of "elements (members) in each system", " interaction between elements" and "theory to describe this interaction".
●Course objectives:
General view of “Evolution of life” will be introduced. Then the mechanism of molecular evolution, especially at genomic and DNA level will be described. Human evolution will be reviewed from viewpoints of genetics, adaptation and environmental changes. Mathematical and theoretical biology and animal behavior will also be reviewed with a special reference to the contribution to development of evolutionary understanding of “life”.
●Contents:
1. Tree of life (1/8・9: Mariko Hasegawa)
2. Basis of molecular evolution (1/29: Yoko Satta)
3. Human evolution – genetics, adaptation, and environment - (1/30: Jun Gojobori)
4. Prediction for future - mathematical and theoretical biology - (2/5: Hisashi Ohtsuki)
5. Animal Behaviour – mechanism and evolution - (2/6: Nobuyuki Kutsukake)
●Lecture materials and readings:
No specific textbook is used. References will be introduced in the lecture when necessary.
●Grades:
The grade is determined by reports/homeworks and attendance at the lectures. 60 points are necessary to get the credit.
☆For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
8. Molecular Cell BiologyⅡ
【fiscal year 2013】
●Course title
●Course title
Molecular Cell BiologyⅡ
●Credit
2 credits
● Lecturer(s):
Contacts to the lecturer :
Professor Hiroyuki Araki (NIG C304)
Professor Hironori Niki (NIG R308)
Professor Takehiko Kobayashi (NIG A301)
Professor Kazuhiro Maeshima (NIG G207)
Professor Tatsuo Fukagawa (NIG C208)
Professor Koichi Kawakami (NIG C115)
Associate Professor Emiko Suzuki (NIG G409)
Associate Professor Yasuo Shirakihara, (NIG C110)
Associate Professor Akatsuki Kimura (NIG A321)
Associate Professor Masato Kanemaki (NIG C318)
Associate Professor Shinya Miyagishima (NIG A325)
Associate Professor Daiju Kitagawa (NIG C316)
Professor Mikio Nishimura (NIBB 403)
Professor Yoshikatsu Matsubayashi (NIBB 201)
Associate Professor Shigenori Nonaka (NIBB 464)
Associate Professor Nobuyuki Shiina (NIBB 335)
Assistant Professor Shoji Mano (NIBB 425)
Assistant Professor Kenji Yamada (NIBB 425)
Assistant Professor Yoshiaki Kamada (NIBB 435)
Assistant Professor Kei Nakayama (NIBB 335)
Assistant Professor Hidefumi Shinohara (NIBB 204)
Professor Tetsuro Kokubo (Yokohama City University)
● Time: (oral and TV) 13:30~15:10 on Friday
●Place: (oral and TV) 3F seminar room of the library in National Institute of Genetics
1F seminar room 4 in National Institute of Basic Biology
●Prerequisites and Styles:
It is desirable to have the basic knowledge corresponding to the lecture of Molecular and Cellular Biology I, but it is not mandatory. It is given as an oral lecture, which will be provided in English if non-Japanese speaking students attend.
●Contents:
Basic features of molecular and cellular biology will be outlined and discussed. These include regulation of gene expression, protein synthesis and protein degradation, protein structure and function, chromosome structure and dynamics, cell cycle regulation, and cell structure.
●Course objectives:
1. Elucidation of biological phenomena in a molecular level
2. Understanding methods to analyze in a molecular level
3. Elucidation of biological phenomena in a cellular level
4. Understanding methods to analyze in a cellular level
●Schedule:
(Oral and TV) Date [lecturers if omnibus] Topic
May 17 Tetsuro Kokubo, Regulation of Transcription
May 24 Nobuyuki Shiina, Regulation of Translation
May 31 Yasuo Shirakihara, Structure and Function of Protein
June 7 Yoshikatsu Matsubayashi & Hidefumi Shinohara, Posttranslational Modifications
June 21 Kazuhiro Maeshima, Structure of Chromosome
June 28 Masato Kanemaki, Replication of Chromosome
July 5 Koichi Kawakami, Recombination and Repair of Chromosome
July 19 Tatsuo Fukagawa, Partition of Chromosomes
October 25 Daiju Kitagawa, Cell Structure I
November 1 Shinya Miyagishima, Cell Structure II
November 15 Akatsuki Kimura, Cytoskelton
January 17 Mikio Nishimura,Organella Dynamics
January 24 Kenji Yamada, Intracellular Transport
January 31 Yoshiaki Kamada & Kei Nakayama, Signal Transduction
February 7 Shigenori Nonaka, Imaging I
February 14 Shoji Mano, Imaging II
February 21 Occasional date
●Lecture materials and readings:
Molecular Biology of the gene 6th ed., J. D. Watson et al., CSHL Press.
Molecular Biology of the cell 5th ed., B. Alberts et al., Garland Science.
Genes, B. Lewin, Prentice Hall.
Introduction to Genetic Analysis, A. J. F. Griffiths, W H Freeman & Co.
The Cell Cycle, D. Morgan, Oxford University Press.
●Grades:
The grades will be A, B, C, and D, which are determined by the quality of the paper, which must be submitted to the lecturer by the provided deadline. The subject(s) of the paper must be one of the four important aspects that are presented in the above Course Objectives.
●Notes:None
For the details of schedule, please refer "Schedule of the classes".

2 credits
● Lecturer(s):
Contacts to the lecturer :
Professor Hiroyuki Araki (NIG C304)
Professor Hironori Niki (NIG R308)
Professor Takehiko Kobayashi (NIG A301)
Professor Kazuhiro Maeshima (NIG G207)
Professor Tatsuo Fukagawa (NIG C208)
Professor Koichi Kawakami (NIG C115)
Associate Professor Emiko Suzuki (NIG G409)
Associate Professor Yasuo Shirakihara, (NIG C110)
Associate Professor Akatsuki Kimura (NIG A321)
Associate Professor Masato Kanemaki (NIG C318)
Associate Professor Shinya Miyagishima (NIG A325)
Associate Professor Daiju Kitagawa (NIG C316)
Professor Mikio Nishimura (NIBB 403)
Professor Yoshikatsu Matsubayashi (NIBB 201)
Associate Professor Shigenori Nonaka (NIBB 464)
Associate Professor Nobuyuki Shiina (NIBB 335)
Assistant Professor Shoji Mano (NIBB 425)
Assistant Professor Kenji Yamada (NIBB 425)
Assistant Professor Yoshiaki Kamada (NIBB 435)
Assistant Professor Kei Nakayama (NIBB 335)
Assistant Professor Hidefumi Shinohara (NIBB 204)
Professor Tetsuro Kokubo (Yokohama City University)
● Time: (oral and TV) 13:30~15:10 on Friday
●Place: (oral and TV) 3F seminar room of the library in National Institute of Genetics
1F seminar room 4 in National Institute of Basic Biology
●Prerequisites and Styles:
It is desirable to have the basic knowledge corresponding to the lecture of Molecular and Cellular Biology I, but it is not mandatory. It is given as an oral lecture, which will be provided in English if non-Japanese speaking students attend.
●Contents:
Basic features of molecular and cellular biology will be outlined and discussed. These include regulation of gene expression, protein synthesis and protein degradation, protein structure and function, chromosome structure and dynamics, cell cycle regulation, and cell structure.
●Course objectives:
1. Elucidation of biological phenomena in a molecular level
2. Understanding methods to analyze in a molecular level
3. Elucidation of biological phenomena in a cellular level
4. Understanding methods to analyze in a cellular level
●Schedule:
(Oral and TV) Date [lecturers if omnibus] Topic
May 17 Tetsuro Kokubo, Regulation of Transcription
May 24 Nobuyuki Shiina, Regulation of Translation
May 31 Yasuo Shirakihara, Structure and Function of Protein
June 7 Yoshikatsu Matsubayashi & Hidefumi Shinohara, Posttranslational Modifications
June 21 Kazuhiro Maeshima, Structure of Chromosome
June 28 Masato Kanemaki, Replication of Chromosome
July 5 Koichi Kawakami, Recombination and Repair of Chromosome
July 19 Tatsuo Fukagawa, Partition of Chromosomes
October 25 Daiju Kitagawa, Cell Structure I
November 1 Shinya Miyagishima, Cell Structure II
November 15 Akatsuki Kimura, Cytoskelton
January 17 Mikio Nishimura,Organella Dynamics
January 24 Kenji Yamada, Intracellular Transport
January 31 Yoshiaki Kamada & Kei Nakayama, Signal Transduction
February 7 Shigenori Nonaka, Imaging I
February 14 Shoji Mano, Imaging II
February 21 Occasional date
●Lecture materials and readings:
Molecular Biology of the gene 6th ed., J. D. Watson et al., CSHL Press.
Molecular Biology of the cell 5th ed., B. Alberts et al., Garland Science.
Genes, B. Lewin, Prentice Hall.
Introduction to Genetic Analysis, A. J. F. Griffiths, W H Freeman & Co.
The Cell Cycle, D. Morgan, Oxford University Press.
●Grades:
The grades will be A, B, C, and D, which are determined by the quality of the paper, which must be submitted to the lecturer by the provided deadline. The subject(s) of the paper must be one of the four important aspects that are presented in the above Course Objectives.
●Notes:None
For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
9. Fundamentals of Biomolecular Science
【fiscal year 2013】
●Course title
●Course title
Fundamentals of Biomolecular Science
●Credit
2 credits
●Lecturer(s):
Shuji Akiyama
(IMS, Myodaiji campus, Research Facilities, 2F)
Koichi Kato
(IMS, Yamate campus building 3, 3F)
Katsuyuki Nishimura
(IMS, Myodaiji campus, Laboratories room 318)
Yuji Furutani
(IMS, Myodaiji campus, Research Facilities, 3F)
●Schedule
*schedule for the second semester in 2013 10/15, 22, 29, 11/5, 12, 19, 26, (12/3)
●Place: Myodaiji campus, Research Facilities 3F, room 301.
●Course objectives:
Core aspects of biophysical chemistry will be overviewed with the life-science student in mind. This course aims at cultivating the fundamentals necessary to complete the advanced courses of Structural Biomolecular Science and of Functional Biomolecular Science. The lectures will be given with life-science examples using a textbook (Physical Chemistry: Principles and Applications in Biological Science).
●Contents:
●Grades: Sufficient attendance to the lecture and a score of some reports
☆For the details of schedule, please refer "Schedule of the classes".

2 credits
●Lecturer(s):
Shuji Akiyama
(IMS, Myodaiji campus, Research Facilities, 2F)
Koichi Kato
(IMS, Yamate campus building 3, 3F)
Katsuyuki Nishimura
(IMS, Myodaiji campus, Laboratories room 318)
Yuji Furutani
(IMS, Myodaiji campus, Research Facilities, 3F)
●Schedule
*schedule for the second semester in 2013 10/15, 22, 29, 11/5, 12, 19, 26, (12/3)
●Place: Myodaiji campus, Research Facilities 3F, room 301.
●Course objectives:
Core aspects of biophysical chemistry will be overviewed with the life-science student in mind. This course aims at cultivating the fundamentals necessary to complete the advanced courses of Structural Biomolecular Science and of Functional Biomolecular Science. The lectures will be given with life-science examples using a textbook (Physical Chemistry: Principles and Applications in Biological Science).
●Contents:
- 1.Biological standard state
- 2.Chemical equilibrium and its temperature dependence
- 3.Kinetics: rates of chemical reactions
- 4.Diffusion
- 5.Active and passive transport across biological membranes
- 6.NMR spectroscopy in structural analyses of biomolecules
- 7.UV/vis, CD, and IR spectroscopies in structural analyses of biomolecules
●Grades: Sufficient attendance to the lecture and a score of some reports
☆For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
10. Bioinformatics
【fiscal year 2013】
●Course title
Bioinformatics
●Course objectives
Introduction to informatic principles behind the –omics and their application to analyze gene network, protein network etc. will be lectured. It is advisable for students to learn the introductory bioinformatic principles.
●Credit 1 (Choose 2 subjects out of 4. (Credit for each subject is 0.5)
●Appropriate grade level and Eligible Departments 1st-5th grades
●Lecturer(s)
Genome Biology (Microorganisms・Plants)
Hironori Niki(Dept. Genetics R302)
Keita Aoki(Dept. Genetics R304)
Tomoya Baba(Dept. Genetics)
Nori Kurata(Dept. Genetics R111)
Kenichi Nomura(Dept. Genetics V101)
Systems Biology
Koichi Kawakami( Dept. Genetics C115)
Akatsuki Kimura(Dept. Genetics A321)
Yuji Kohara (Dept. Genetics C709)
Introduction to Mathematical Biology
Akira Sasaki (Dept. Evolutionary Studies of Biosystems)
Biological Information Processing
Kunihiko Sadakane (Dept. Infomatics)
●Schedule
For the fiscal year 2013
Genome Biology (Microorganisms・Plants) (Dept. Genetics ) >Syllabus
6/10, 17, 7/22, 29 Monday 10:50-12:30
Systems Biology (Dept. Genetics ) >Syllabus
1. May 13: Akatsuki Kimura: Overview of systems biology and its approaches.
2. May 20: Akatsuki Kimura: On the methods of systems biology: focusing on theoretical
analyses and quantitative measurements
3. May 27: Yuji Kohara: Understanding life as a system: Contributions and perspectives of
the ‘omics’-approach.
4. June 3: Koichi Kawakami: Understanding life as a system: From gene function to nervous system.
Introduction to Mathematical Biology (Dept. Evolutionary Studies of Biosystems)
10/9, 10
Biological Information Processing (Dept. Infomatics)
11/7,14,21,28
For the details of schedule, please refer "Schedule of the classes".

●Course title
Bioinformatics
●Course objectives
Introduction to informatic principles behind the –omics and their application to analyze gene network, protein network etc. will be lectured. It is advisable for students to learn the introductory bioinformatic principles.
●Credit 1 (Choose 2 subjects out of 4. (Credit for each subject is 0.5)
●Appropriate grade level and Eligible Departments 1st-5th grades
●Lecturer(s)
Genome Biology (Microorganisms・Plants)
Hironori Niki(Dept. Genetics R302)
Keita Aoki(Dept. Genetics R304)
Tomoya Baba(Dept. Genetics)
Nori Kurata(Dept. Genetics R111)
Kenichi Nomura(Dept. Genetics V101)
Systems Biology
Koichi Kawakami( Dept. Genetics C115)
Akatsuki Kimura(Dept. Genetics A321)
Yuji Kohara (Dept. Genetics C709)
Introduction to Mathematical Biology
Akira Sasaki (Dept. Evolutionary Studies of Biosystems)
Biological Information Processing
Kunihiko Sadakane (Dept. Infomatics)
●Schedule
For the fiscal year 2013
Genome Biology (Microorganisms・Plants) (Dept. Genetics ) >Syllabus
6/10, 17, 7/22, 29 Monday 10:50-12:30
Systems Biology (Dept. Genetics ) >Syllabus
1. May 13: Akatsuki Kimura: Overview of systems biology and its approaches.
2. May 20: Akatsuki Kimura: On the methods of systems biology: focusing on theoretical
analyses and quantitative measurements
3. May 27: Yuji Kohara: Understanding life as a system: Contributions and perspectives of
the ‘omics’-approach.
4. June 3: Koichi Kawakami: Understanding life as a system: From gene function to nervous system.
Introduction to Mathematical Biology (Dept. Evolutionary Studies of Biosystems)
10/9, 10
Biological Information Processing (Dept. Infomatics)
11/7,14,21,28
For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF
11. Origin of Life
【fiscal year 2013】
●Course title
Origin of Life
●Course objectives:
Where, when and how the molecules essential for the primitive life were born, how a self-replicating capacity was acquired, how the primitive life evolved to more complex organisms will be broadly discussed.
●Credit 1
●Appropriate grade level and Eligible Departments 1st-5th grades
●Lecturer(s)
Takashi Gojoubori(Dept. Genetics)
Shinya Miyagishima(Dept. Genetics)
Ken Takai(JAMSTEC)
Motohide Tamura (The Univ. of Tokyo)
Takeshi Kakegawa (Tohoku Univ.)
Hiroaki Suga (The Univ. of Tokyo)
Hiroyuki Araki(Dept. Genetics)
Toshitaka Fujisawa (CPIS, SOKENDAI)
●Schedule
For the fiscal year 2013
5/22 Evolution of Life Takashi Gojoubori
6/17 Energy Metabolism: Mitochondria and Chloroplasts Shinya Miyagishima
10/23 Extremophiles Ken Takai
10/31 Astrobiology Motohide Tamura
11/11 Birth of Primitive Life Substances Takeshi Kakegawa
11/20 The RNA World Hiroaki Suga
1/16 Replication Phenomenon and its Origin Hiroyuki Araki
For the details of schedule, please refer "Schedule of the classes".

●Course title
Origin of Life
●Course objectives:
Where, when and how the molecules essential for the primitive life were born, how a self-replicating capacity was acquired, how the primitive life evolved to more complex organisms will be broadly discussed.
●Credit 1
●Appropriate grade level and Eligible Departments 1st-5th grades
●Lecturer(s)
Takashi Gojoubori(Dept. Genetics)
Shinya Miyagishima(Dept. Genetics)
Ken Takai(JAMSTEC)
Motohide Tamura (The Univ. of Tokyo)
Takeshi Kakegawa (Tohoku Univ.)
Hiroaki Suga (The Univ. of Tokyo)
Hiroyuki Araki(Dept. Genetics)
Toshitaka Fujisawa (CPIS, SOKENDAI)
●Schedule
For the fiscal year 2013
5/22 Evolution of Life Takashi Gojoubori
6/17 Energy Metabolism: Mitochondria and Chloroplasts Shinya Miyagishima
10/23 Extremophiles Ken Takai
10/31 Astrobiology Motohide Tamura
11/11 Birth of Primitive Life Substances Takeshi Kakegawa
11/20 The RNA World Hiroaki Suga
1/16 Replication Phenomenon and its Origin Hiroyuki Araki
For the details of schedule, please refer "Schedule of the classes".
⇒ Syllabus
PDF












